Ion Exchange Kit For MAb Separations
|P/N||Phase||ID × Length (mm)||Column Material|
|MABIEXKITP-0000||Antibodix™ WCX-NP5||4.6 × 250 mm||PEEK|
|Proteomix® SCX-NP5||4.6 × 250 mm||PEEK|
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Both Antibodix™ WCX and Proteomix® SCX phases are comprised of rigid, spherical, highly cross-linked non-porous poly(styrene divinylbenzene) (PS/DVB) beads. The PS/DVB particle surface is grafted with a highly hydrophilic, neutral polymer layer with a thickness in the range of nanometers. The hydrophobic PS/DVB resin surface is totally covered by a hydrophilic coating which eliminates non-specific bindings with antibody proteins, leading to high
efficiency and high recovery separations.
Antibodix™ WCX phase
On top of the hydrophilic layer, weak cation-exchange carboxylate (-COOH) functional groups are attached via a proprietary chemistry, resulting in a high capacity ion-exchange layer.
Proteomix® SCX phase
On top of the hydrophilic layer, strong cation-exchange sulfonate (-SO3H) functional groups are attached via a proprietary chemistry, resulting in a high capacity ion-exchange layer.