Description | Packing | Characteristics | Application | Order Info | Downloads |
Using porous polyacrylate particle as the support, Generik MC-SCX, WCX, SAX and WAX ion-exchange media are synthesized. Generik MC-SCX is a strong cation exchanger with sulfonate functional group. Generik MC-WCX is a weak cation exchanger with carboxylate functional group. Generik MC-SAX is a strong anion exchanger with quaternary ammonium functional group. Generik MC-WAX is a weak anion exchanger with tertiary amine functional group. The controlled manufacturing process guarantees high batch-to-batch reproducibility. Their high capacity and high mechanical strength enable those media ideal for preparative separation and purification of proteins, peptides, nucleic acids, antibodies, and other biopharmaceuticals.
Typical Properties
These properties are typical but do not constitute specifications.
Products | Generik MC-SAX | Generik MC-SCX | Generik MC-WAX | Generik MC-WCX |
Ion-exchanger type | Strong anion | Strong cation | Weak anion | Weak cation |
Functional group | -N+(CH3)3 | -SO3- | -HN+ (C2H5)2 | -CH2COO- |
Ionic capacity (meq/mL) | 0.32-0.37 | 0.18-0.22 | 0.15-0.21 | 0.14-0.19 |
Average particle size (µm) | 30, 60 | 30, 60 | 30, 60 | 30, 60 |
Average pore size (Å) | 800 | 800 | 800 | 800 |
Storage solvent | 20% ethanol | 20% ethanol | 20% ethanol | 20% ethanol |
DBC* | 45 mg/mL | 42 mg/mL | 32 mg/mL | 33 mg/mL |
Chemical stability | Commonly used aqueous buffers, such as phosphate, Tris, acetate. |
Cleaning solutions | 0.5 M HCl, 0.5 M NaOH |
pH stability | 2~13 | 2~13 | 2~13 | 2~13 |
Volume change | pH 2-13 | <1% | <1% | <1% | <1% |
0.01-1.0M NaCl | <1% | <1% | <1% | <1% |
Regeneration salt | 1-2 M NaCl | 1-2 M NaCl | 1-2 M NaCl | 1-2 M NaCl |
*DBC (Dynamic Binding Capacity) measurement method: for Generik MC-SAX and Generik MC-WAX, 10.0 mg/mL of BSA in 50 mM Tris buffer, pH 8.7, column size 10×150 mm, linear flow rate 212 cm/h, 10% breakthrough. For Generik MC-SCX and Generik MC-WCX, 10.0 mg/mL of lysozyme in 50 mM phosphate buffer, pH 6.0, column size 10×150 mm, linear flow rate 230 cm/h, 10% breakthrough.
- High chemical stability for low leaching
- Spherical particles with narrow particle size distribution
- High accessible surface area and high loading capacity
- High retentativity and selectivity
- Wide pH applications (pH=2-13)
- High lot to lot consistency
- Available from grams to multi-Kilogram
- Purification of proteins, peptides, proteins, nucleic acids, oligonucleotides and antibodies
- Suitable for heparin purification
- Solid phase extraction
- Flash chromatography
- Process purification
Phase | Particle Size | Pore Size | P/N |
Polar MC30-SCX | 30 µm | 800 Å | 283030-0000 |
Polar MC30-WCX | 30 µm | 800 Å | 284030-0000 |
Polar MC30-SAX | 30 µm | 800 Å | 285030-0000 |
Polar MC30-WAX | 30 µm | 800 Å | 286030-0000 |
Polar MC60-SCX | 60 µm | 800 Å | 283060-0000 |
Polar MC60-WCX | 60 µm | 800 Å | 284060-0000 |
Polar MC60-SAX | 60 µm | 800 Å | 285060-0000 |
Polar MC60-WAX | 60 µm | 800 Å | 286060-0000 |
Generik MC30-SCX | 30 µm | 800 Å | 273030-0000 |
Generik MC30-WCX | 30 µm | 800 Å | 274030-0000 |
Generik MC30-SAX | 30 µm | 800 Å | 275030-0000 |
Generik MC30-WAX | 30 µm | 800 Å | 276030-0000 |
Generik MC60-SCX | 60 µm | 800 Å | 273060-0000 |
Generik MC60-WCX | 60 µm | 800 Å | 274060-0000 |
Generik MC60-SAX | 60 µm | 800 Å | 275060-0000 |
Generik MC60-WAX | 60 µm | 800 Å | 276060-0000 |
MabPurix Protein A | 45-165 µm | | 281085-0000 |
Package size: 10mL, 100mL, 250mL, 500mL, 1L, 10L, 50L and others for request.
The resins are stored and shipped in 20% ethanol in water. Dry resin is available upon request.
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