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Size Exclusion:
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Ion Exchange: Proteomix Antibodix Proteomix AAV SAX Reversed phase: Proteomix RP Bio-C4 Hydrophobic Interaction: Proteomix HIC
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Application Note
Featured Application Notes
All Application Notes
App ID | Title |
ZM1019 | Analytical Characterization of Antibody Drug Conjugates | Size Exclusion@Ion Exchange@Reversed PhaseZenix-C@Proteomix@Proteomix RPMethod Optimization@Volatile Buffer@Packing Chemistry@Fast Assay@MAb Fragment@Charge Variants@Aggregates@Resolution@Competition Comparison@Orthogonal MethodHPLC@LCMS1
LR2023011394 | Literature Reference: Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody Drug Conjugates | SECZenix-C SEC-300gsADCs@Glycosite-Specific Antibody Drug@Site-Specific ADCs on Sepax Analytical SEC HPLC1
EM1003 | Herceptin Analysis on ZenixTM SEC-300 (7830) | Ion ExchangeZenixHerceptin AnalysisHPLC1
WM1002 | ADC Separation on Unix-C SEC-300 | Size ExclusionUnix-CResolution@Aggregates@Competition Comparison@Column Stability@Lot to Lot@Particle Size Impact@LoadingUHPLC1
ZM1024 | Intact MAb, ADC and their Fragment Analysis with SEC-MS | Size Exclusion@Size Exclusion@Size Exclusion@Size ExclusionZenix@Zenix-CMAb Fragment@Resolution@Volatile Buffer@Method Optimization HPLC@LCMS1
ZM1023 | ADC vs. Free Drug Analysis | Size Exclusion@Size Exclusion@Size ExclusionZenix@Zenix-CResolution@Volatile Buffer@Pore Size Selection@Fast Assay@Method Optimization@Loading HPLC@LCMS1
PM1016 | Intact MAb, ADC and their Fragments Analysis on RP LC/MS | Hydrophobic Interaction@Reversed Phase@Reversed PhaseProteomix HIC@Proteomix RPMAb Fragment@Resolution@Volatile Buffer@Method OptimizationHPLC@LCMS1
ZM1022 | MAb/ADC Fragment Separation after IDeS Digestion | Size Exclusion@Size Exclusion@Hydrophobic Interaction@Reversed PhaseZenix@Zenix-C@Proteomix HIC@Proteomix RPMAb Fragment@Resolution@Volatile BufferHPLC/LCMS1
HICM1001 | ADC/MAb Separation on Proteomix HIC | Hydrophobic InteractionProteomix@Proteomix HICLot to Lot@Competition Comparison@ResolutionHPLC1
PM1013 | Intact and Reduced MAb/ADC and MAb Fragment Separation on RP | Reversed PhaseProteomix@Proteomix RPMethod Optimization@Volatile Buffer@Packing Chemistry@Fast Assay@MAb Fragment@Orthogonal MethodHPLC@LCMS@NanoLC1
EM1004 | Herceptin-Lysine ADC Analysis by Zenix-C and TSKgel | Size ExclusionZenix-CCompetition Comparison@Resolution@Packing Chemistry@Aggregates@Method OptimizationHPLC1
PM1011 | Herceptin-Cysteine ADC Charge Variants Separation on SCX | Ion ExchangeProteomixCharge VariantsHPLC1
ZM1018 | MAb and its ADCs Separation on SEC | Size ExclusionZenix@Zenix-CResolution@Packing Chemistry@Aggregates@Method OptimizationHPLC1
EM1002 | ADC Analysis on Zenix-C SEC | Size ExclusionZenix@Zenix-CResolution@Packing Chemistry@Aggregates@Method OptimizationHPLC1
LR202202170 | Literature Reference: Single Domain Antibodies as Carriers for Intracellular Drug Delivery: A Proof of Principle Study | SECZenix-C SEC-300ADC, LC-MS Analysis, Organix Mobile Phase ACN:TFA:WaterHPLC@LC-MS1
LR202202664 | Literature Reference: Homogeneous Antibody-Drug Conjugates: DAR 2 Anti-HER2 Obtained by Conjugation on Isolated Light Chain Followed by mAb Assembly | Size Exclusion, Hydrophobic InteractionZenix-C SEC-300@Proteomix HIC Butyl-NP5ADC, Heavy Chain and Light Chain AnalysisHPLC@HPLC1
LR202202105 | Literature Reference: In-situ Reverse Phased HPLC Analysis of Intact Antibody-Drug Conjugates | Reversed PhaseProteomix RPADC (Antibody Drug Conjugate)HPLC2
LR202202620 | Literature Reference: Design and Characterization of Homogenous Antibody-drug Conjugates with a Drug-to-Antibody Ratio of One Prepared Using an Engineered Antibody and a Dual-maleimide Pyrrolobenzodiazepine Dimer | Hydrophobic InteractionProteomix HICHydrophobic Interaction, Site-Specific ADC, DARHPLC2
LR202202670 | Literature Reference: Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody-Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine Conjugation | Hydrophobic InteractionProteomix HICHydrophobic Interaction, ADCHPLC2
LR2023101483 | Literature Reference: Novel Thienoduocarmycin-trastuzumab ADC Demonstrates Strong Anti-tumor Efficacy | HICProteomix HICThienoduocarmycin-trastuzumab ADCHPLC2
LR2022081354 | Design and Characterization of Immune-Stimulating Imidazo45-cquinoline Antibody Drug Conjugates | RPProteomix RPADC Free Drug Analysis on Sepax Analytical RP ColumnHPLC@UHPLC2