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Technical Support
(877) SEPAX-US, press 3  TechSupport@sepax-tech.com |
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Analytical and Preparative Size Exclusion
Unix™,
Unix™-C,
Zenix®/
Zenix®-C,
SRT®/
SRT®-C,
SRT®-10/
SRT®-10C,
and Nanofilm®
are nine SEC product lines developed based on innovative surface coating and particle technologies comprised of uniform, hydrophilic, and neutral nanometer thick films chemically bonded on 1.8 µm, 3 µm, 5 µm, or 10 µm high purity and mechanically stabilized silica.
Utilizing two unique surface coating technologies - stand-up monolayer bonded on porous silica for Unix™, Zenix®, SRT® and SRT®-10; and lay-down monolayer on porous silica for Unix™-C, Zenix®-C, SRT®-C, and SRT®-10C, Sepax offers surface chemistry choices based on sample type and sample hydrophobicity in order to achieve high resolution performance separation.
Find Your Right Particle Size
| Product Line | Unix™/Unix™-C | Zenix®/Zenix®-C | SRT®/SRT®-C | SRT®-10/SRT®-10C |
|---|---|---|---|---|
| Particle size | 1.8 µm | 3 µm | 5 µm | 10 µm |
| Pore size (Å) | 200, 300 | 80, 100, 150, 300 | 100, 150, 300, 500, 1000, 2000 | 100, 300, 500, 1000 |
| Resolution & Efficiency | Highest | Higher | High | Purification |
| Instruments | UHPLC, HPLC | HPLC, UHPLC | HPLC, FPLC | HPLC, FPLC |
Find Your Suitable Surface Chemistry
| Product Line | Unix™, Zenix®, SRT®, SRT®-10 | Unix™-C, Zenix®-C, SRT®-C, SRT®-10C |
|---|---|---|
| Surface structure | Chemically bonded stand-up monolayer | Chemically bonded lay-down monolayer |
| Applications | Non-Hydrophobic samples like Monoclonal antibodies, proteins, peptides, nucleic acids, oligonucleotides, virus, and water-soluble polymers | Ideal for "tough samples" like hydrophobic samples or highly glycosylated samples such as insulin, ADC, hydrophobic mAb, pegylated peptides and proteins. Can also be used as a versatile column if screening many different types of sample. |
Nanofilm® is made with a special stationary phase - a polymeric brush coating. Such a neutral, hydrophilic polymer coating is suitable for positively charged proteins and hydrophobic proteins, such as membrane proteins.
| Product Line | Nanofilm® |
|---|---|
| Particle size | 5 µm |
| Pore size (Å) | 150, 250, 450 |
| Efficiency | High |
| Selectivity | Same for SRT® and Zenix™ |
| Surface structure | Chemically bonded polymeric coating |
| Recommended Sample Types | Highly positively charged proteins, hydrophobic proteins like membrane protein |