are nine SEC product lines developed based on innovative surface coating and particle technologies comprised of uniform, hydrophilic, and neutral nanometer thick films chemically bonded on 1.8 µm, 3 µm, 5 µm, or 10 µm high purity and mechanically stabilized silica.
Utilizing two unique surface coating technologies - stand-up monolayer bonded on porous silica for Unix™, Zenix®, SRT® and SRT®-10; and lay-down monolayer on porous silica for Unix™-C, Zenix®-C, SRT®-C, and SRT®-10C, Sepax offers surface chemistry choices based on sample type and sample hydrophobicity in order to achieve high resolution performance separation.
Find Your Right Particle Size
|Particle size||1.8 µm||3 µm||5 µm||10 µm|
|Pore size (Å)||200, 300||80, 100, 150, 300||100, 150, 300, 500, |
|100, 300, 500, 1000|
|Resolution & |
|Instruments||UHPLC, HPLC||HPLC, UHPLC||HPLC, FPLC||HPLC, FPLC|
Find Your Suitable Surface Chemistry
||Unix™, Zenix®, SRT®, SRT®-10
||Unix™-C, Zenix®-C, SRT®-C, SRT®-10C
||Chemically bonded stand-up monolayer
||Chemically bonded lay-down monolayer
||Non-Hydrophobic samples like Monoclonal antibodies, proteins, peptides, nucleic acids, oligonucleotides, virus, and water-soluble polymers
||Ideal for "tough samples" like hydrophobic samples or highly glycosylated samples such as insulin, ADC, hydrophobic mAb, pegylated peptides and proteins. Can also be used as a versatile column if screening many different types of sample.
Nanofilm® is made with a special stationary phase - a polymeric brush coating. Such a neutral, hydrophilic polymer coating is suitable for positively charged proteins and hydrophobic proteins, such as membrane proteins.
|Particle size||5 µm|
|Pore size (Å)||150, 250, 450|
|Selectivity||Same for SRT® and Zenix™|
|Surface structure||Chemically bonded polymeric coating|
|Recommended Sample Types||Highly positively charged proteins, hydrophobic proteins like membrane protein|