Sepax Monomix Mab60-SP is is based on hydrophilic treated polymethacrylate. .The resin has highly uniformly dispersed (D90/D10<1.3) particle size of 60 μm, and pore size of 1000 Å, with excellent physical and chemical stability as well as high loading capacity with DBC greater than 80 mg/mL.
The resin is surface-treated through Sepax’s proprietary method, and has increased surface hydrophilicity and largely avoided non-specific binding to biological samples. By proprietary surface modification technology, ion-exchange functional groups are bonded on the surface of hydrophilic substrates to obtain strong cation exchange functional groups (SP) and form an ion exchange layer of high functional group density.
The Monomix Mab60-SP resin can be widely used in the separation and purification of biological samples such as antibodies, vaccines, insulins, proteins, nucleic acids, and heparins
High binding capacity and excellent biocompatibility
Capable of withstanding high pressure and high flow rate due to rigid base bead matrix
High separation resolution, efficiency and recovery.
High lot-to-lot consistency
Easy to scale up
Highly hydrophilic surface with minimal non-specific binding
Small volume change under normal packing conditions
Supply capacity: >100L per batch
Average Particle Size
Average Pore Size (Å)
Dynamic loading capacity
≥ 60 mg Lysozyme /mL of resin
Maximum operating pressure
≤1.0 M NaOH
20% ethanol, 2% benzyl alcohol or 10 mM NaOH in aqueous solution
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Monomix Mab60-SP, Pre-Packed Column (7.5 x 100 mm, 4.2mL)