HP-C18(2) uses a proprietary ODS bonding chemistry to a high surface area silica gel to achieve long retention time and high loading capability. The ODS density is specially designed to achieve optimal selectivity for both hydrophobic and hydrophilic compounds. The proprietary endcapping chemistry maximizes consumption of silanol groups on the silica surface, and minimizes the free silanol groups to undetectable level. Such unique bonding chemistry allows the phase to achieve high peak symmetry, even for basic compounds. HP-C18(2) phase is compatible with 100% aqueous mobile phases.
Silica:
Spherical, high purity (<10 ppm metals)
Pore size:
100 Å
Particle size:
3 and 5 µm
Pore volume:
1.1 ml/g
Surface area:
450 m²/g
Phase structure:
Special bonding density and proprietary endcapping
% Carbon:
17%
Specially designed ODS density bonded to highly pure silica
Free silanol groups on silica surface is minimized to undetectable level
High loadability
Compatible with 100% aqueous mobile phases
High column-to-column reproducibility
Optimal selectivity for both hydrophobic and hydrophilic compounds
Available for both analytical and preparative
Suitable for separations of acidic, neutral and basic organic compounds, as well as pharmaceuticals, peptides, peptide mapping, and others
Recommended for separations in organic or mixed organic/aqueous mobile phases
[1] Guard column [2] One-piece PEEK coupler, recommended to connect columns in series. [3] PEEK/Stainless Steel coupler, recommended to connect columns of IDs > 7.8 mm in series. [4] Column coupler with 10cm length flexible tubing,10-32 fitting with 1/16 OD PEEK tubing. Recommended to connect analytical columns in series
[1] Guard column [2] One-piece PEEK coupler, recommended to connect columns in series. [3] PEEK/Stainless Steel coupler, recommended to connect columns of IDs > 7.8 mm in series. [4] Column coupler with 10cm length flexible tubing,10-32 fitting with 1/16 OD PEEK tubing. Recommended to connect analytical columns in series
