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Representative Literature References

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Product PN Separation Mode
 Broad Sample Type Specific Sample
Year Product PN Sep. Mode Broad Sample Category Specific Sample Title
2024Proteomix HIC Butyl-NP5431NP5-4610HICAntibodyProtein Tyrosine SulfationStructure-function Relationship Study for Sulfated Protein Therapeutics Using Hydrophobic Interaction Chromatography and Mass Spectrometry
2024Proteomix SCX-NP3401NP3-4615IEXAntibodyMonoclonal AntibodiesOnline Multimethod Platform for Comprehensive Characterization of Monoclonal Antibodies in Cell Culture Fluid a Single Sample Injection - Intact Protein Workflow
2024SRT SEC-500215500-4630SECAntibodyComplex with mAbCharacterization of Large Immune Complexes with Size Exclusion Chromatography and Native Mass Spectrometry Supplemented with Gas Phase Ion Chemistry
2024Unix-C SEC-300231300-4615SECAntibodyHIV-1 Env AntibodyAbsolute quantitation of binding antibodies from clinical samples
2023Proteomix HIC Butyl-NP5N/AHICAntibodyMAbAntibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers
2022SRT-10C SEC-300239300-30030SECAntibodymAbDevelopment of a robust and semi-automated two-step antibody purification process
Mabs. Vol. 13. No. 1. Taylor & Francis, 2021.
2021SRT SEC-500215500-4630SECAntibodyIgGComparative Analysis of Antibodies and Heavily Glycosylated Macromolecular Immune Complexes by Size-Exclusion Chromatography Multi-Angle Light Scattering, Native Charge Detection Mass Spectrometry, and Mass Photometry
Analytical Chemistry (2021).
2021Proteomix SCX-NP10, Antibodix WCX-NP5401NP10-4625, 401NP10-10025, 401NP10-21225, 401NP10-10005, 602NP5-4625IEXAntibodyHuman IgG1 MabA novel twin-column continuous chromatography approach for separation and enrichment of monoclonal antibody charge variants
Engineering in Life Sciences Volume21, Issue 6 June 2021 Pages 382-391
2020Proteomix HIC butyl-NP5431NP5-4603HICAntibodymAbAn Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19
bioRxiv (2020).
2020Proteomix SCX-NP5401NP5-4610IEXAntibodyABF710Analytical and Functional Similarity Assessment of ABP 710, a Biosimilar to Infliximab Reference Product
Saleem, Ramsey, et al. "Analytical and functional similarity assessment of ABP 710, a biosimilar to infliximab reference product." Pharmaceutical research 37.6 (2020): 1-23.
2020Proteomix SCX NP5401NP5-4610IEXAntibodyinfliximabAnalytical and Functional Similarity Assessment of ABP 710, a Biosimilar to Infliximab Reference Product
Pharmaceutical research 37.6 (2020): 1-23.
2020Proteomix SCX-NP5, PEEK401NP5P-4625IEXAntibodyIgG2 isoformsOptimizing TNFR2 antagonism for immunotherapy with tumor microenvironment specificity
Journal of Leukocyte Biology Volume 107, Issue 6 June 2020 Pages 971-980
2020SRT-10C SEC-100239100-10030SECAntibodySynthetic nanobodiesGeneration of synthetic nanobodies against delicate proteins
Nature Protocols volume 15, pages1707–1741 (2020)
2019Proteomix HIC butyl-NP5431NP5-4603HICAntibodymAbs with Vκ or Vλ variabilityAffinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability
Cell reports 28.13 (2019): 3300-3308.
2018SRT SEC-500215500-4630SECAntibodyα4β2–Fab complexesStructural principles of distinct assemblies of the human α4β2 nicotinic receptor
Nature volume 557, pages261–265 (2018)
2018SRT-C SEC-300235300-4630SECAntibodyAntibodyMobile Affinity Sorbent Chromatography
Anal. Chem. 2018, 90, 3, 1668–1676
2018Zenix-C SEC-300N/ASECAntibodyN/AA bispecific antibody that targets IL-6 receptor and IL-17A for the potential therapy of patients with autoimmune and inflammatory diseases
The Journal of Biological Chemistry 293, 9326-9334. 10.1074/jbc.M117.818559
2018Zenix SEC-300N/ASECAntibodyN/AAn ambient temperature-stable antitoxin of nine co-formulated antibodies for botulism caused by serotypes A, B and E
PLOS ONE 13(5): e0197011. https://doi.org/10.1371/journal.pone.0197011
2018N/AN/AIEXAntibodyN/AInfluence of disulfide bond isoforms on drug conjugation sites in cysteine-linked IgG2 antibody-drug conjugates
mAbs. 2018;10(4):583-595. doi:10.1080/19420862.2018.1440165.
2017Zenix SEC-300 & Proteomix HIC butyl-NP5213300-4630, 431NP5-4603SECAntibodyIgGBiophysical properties of the clinical-stage antibody landscape
Proceedings of the National Academy of Sciences 114.5 (2017): 944-949.
2017Proteomix HIC butyl-NP5431NP5-4603HICAntibodymAbsPrediction of Delayed Retention of Antibodies in Hydrophobic Interaction Chromatography from Sequence using Machine Learning
Bioinformatics 33.23 (2017): 3758-3766.
2017N/AN/AIEXAntibodyN/AOn-Line Ion Exchange Liquid Chromatography as a Process Analytical Technology for Monoclonal Antibody Characterization in Continuous Bioprocessing
Anal. Chem. 89, 21, 11357-11365
2017N/AN/AIEXAntibodyN/APreclinical Characterization of CTL-1, A Biosimilar Anti-EGFR Monoclonal Antibody for Cetuximab
SM J Bioequiv Availab 1, no. 1 (2017): 1003.
2017Zenix-C SEC-300N/ASECAntibodyN/AEfficient generation of single domain antibodies with high affinities and enhanced thermal stabilities
Scientific Reports 7, Article number: 5794 (2017) doi:10.1038/s41598-017-06277-x
2016Zenix SEC-300N/ASECAntibodyN/AAnalysis of monoclonal antibody oxidation by simple mixed mode chromatography
Journal of Chromatography A Volume 1431, 29 January 2016, Pages 154–165
2016Zenix SEC-300N/ASECAntibodyN/AImmunotargeting of Integrin α6β4 for Single-Photon Emission Computed Tomography and Near-Infrared Fluorescence Imaging in a Pancreatic Cancer Model
Molecular Imaging January-December 2016 vol. 15 1536012115624917
2015Zenix SEC-300N/ASECAntibodymAbs of 12 varietiesA novel screening method to assess developability of antibody-like molecules
2015Zenix-C SEC-300N/ASECAntibodyN/AIntrinsic fluorescence-based at situ soft sensor for monitoring monoclonal antibody aggregation
Biotechnology Progress
2014Zenix SEC-300N/ASECAntibodyN/AAntitumor efficacy of a bispecific antibody that targets HER2 and activates T cells.
Cancer Res. 2014 Oct 1;74(19):5561-71. doi: 10.1158/0008-5472.CAN-13-3622-T.
2012Zenix SEC-300N/ASECAntibodyN/AAglycosylated antibodies and antibody fragments produced in a scalable in vitro transcription-translation system
mAbs, Volume 4, Issue 2, pages 217-225
2011Zenix SEC-300N/ASECAntibodyN/AAntibody solubility behavior in monovalent salt solutions reveals specific anion effects at low ionic strength
Journal of Pharmaceutical Sciences, Volume 101, Issue 3, pages 965-977
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