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Representative Literature References

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Year Product Sample Title
2015ZenixProteinApplication of coupled affinity-sizing chromatography for the detection of proteolyzed HSA-tagged proteins
Protein Expr Purif. 2015 Apr;108:80-4
2018ZenixProteinA Haloalkane Dehalogenase from a Marine Microbial Consortium Possessing Exceptionally Broad Substrate Specificity
Appl. Environ. Microbiol. January 2018 vol. 84 no. 2 e01684-17
2015Zenix SECAntibodyA novel screening method to assess developability of antibody-like molecules
MAbs. 2015 May 11:0
2016Zenix SEC-100Dendritic Polymer, Polymeric NanomedicinesIn vivo comparative study of distinct polymeric architectures bearing a combination of paclitaxel and doxorubicin at a synergistic ratio
J Control Release. 2017 Jul 10;257:118-131. doi: 10.1016/j.jconrel.2016.06.037
2014Zenix SEC-100PolymerAnticancer polymeric nanomedicine bearing synergistic drug combination is superior to a mixture of individually-conjugated drugs
J Control Release, 187, 145-57
2016Zenix SEC-100WastewaterCharacterization of a hybrid powdered activated carbon-dynamic membrane bioreactor (PAC-DMBR) process with high flux by gravity flow: Operational performance and sludge properties
Bioresource Technology, Volume 223, 2017, Pages 65-73, ISSN 0960-8524,
2014Zenix SEC-100, 4.6 x 150LiposomeFolate-Targeted Liposome Encapsulating Chitosan/Oligonucleotide Polyplexes for Tumor Targeting
AAPS PharmSciTech, 15(5), 1087-92
2014Zenix SEC-100, 4.6 x 300 & 2.1 x 50ProteinInfluence of molecular weight on intracellular antioxidant activity of invasive silver carp (Hypophthalmichthys molitrix) protein hydrolysates
Journal of Functional Foods
2016Zenix SEC-150Others, ProteinDetermination of residual dextran sulfate in protein products by SEC–HPLC
Journal of Chromatography B Volume 1011, 1 February 2016, Pages 89–93
2017Zenix SEC-150Polymer of CefmetazoleDevelopment and Validation of a High-Performance Size-Exclusion Chromatography Method for Polymer Determination in Cefmetazole Sodium for Injection
Acta Chromatographica 29(2017)2, 193–205 DOI: 10.1556/1326.2017.29.2.4
2015Zenix SEC-150ProteinNanosecond electric pulses deprive zinc ions of carboxypeptidase G2
Bioelectrochemistry 101 (2015) 42–45
2017Zenix SEC-150ProteinHow to Avoid Size Mismatch Between Solutes and Column Pores for Optimum HPLC Performance
American Laboratory June/July 2017
2016Zenix SEC-300AntibodyImmunotargeting of Integrin α6β4 for Single-Photon Emission Computed Tomography and Near-Infrared Fluorescence Imaging in a Pancreatic Cancer Model
Molecular Imaging January-December 2016 vol. 15 1536012115624917
2016Zenix SEC-300AntibodyAnalysis of monoclonal antibody oxidation by simple mixed mode chromatography
Journal of Chromatography A Volume 1431, 29 January 2016, Pages 154–165
2018Zenix SEC-300AntibodyAn ambient temperature-stable antitoxin of nine co-formulated antibodies for botulism caused by serotypes A, B and E
PLOS ONE 13(5): e0197011.
2014Zenix SEC-300AntibodyAntitumor efficacy of a bispecific antibody that targets HER2 and activates T cells.
Cancer Res. 2014 Oct 1;74(19):5561-71. doi: 10.1158/0008-5472.CAN-13-3622-T.
2015Zenix SEC-300Bispecific AntibodyProtein design of IgG/TCR chimeras for the co-expression of Fab-like moieties within bispecific antibodies
mAbs 7:2, 364--376; March/April 2015; © 2015 Eli Lilly Biotechnology Center
2016Zenix SEC-300Bispecific AntibodyAn efficient route to bispecific antibody production using single-reactor mammalian coculture
MAbs. 2016 Nov/Dec;8(8):1487-1497.
2017Zenix SEC-300OligodeoxynucleotidesAn Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications
Molecular Therapy - Nucleic Acids , Volume 9 , 284 - 293
2013Zenix SEC-300PEG/PEGylated ProteinOptimization of random PEGylation reactions by means of high throughput screening
Biotechnology and Bioengineering, Volume 111, Issue 1, pages 104-114
2016Zenix SEC-300ProteinRapid analysis of protein expression and solubility with the SpyTag–SpyCatcher system
Protein Expression and Purification Volume 117, January 2016, Pages 44–51
2013Zenix SEC-300, 4.6 x 250ADCTrastuzumab-Doxorubicin Conjugate Provides Enhanced Anti-Cancer Potency and Reduced Cardiotoxicity
Journal of Cancer Therapy, Vol.4 No.1
2012Zenix SEC-300, 4.6 x 300ProteinAccurate retention time determination of co-eluting proteins in analytical chromatography by means of spectral data
Biotechnology and Bioengineering, Volume 110, Issue 3, pages 683-693,
2012Zenix SEC-300, 4.6 x 300 & 4.6 x 150ProteinRapid quantification of protein–polyethylene glycol conjugates by multivariate evaluation of chromatographic data
Journal of Chromatography A, Volume 1257, Pages 41-47
2013Zenix SEC-300, 7.8 x 150Fusion ProteinCoupled affinity and sizing chromatography: A novel in-process analytical tool to measure titer and trend Fc-protein aggregation
Journal of Immunological Methods, Volume 393, Issues 1-2, Pages 81-85
2014Zenix SEC-300, 7.8 x 150 HTPProteinHigh-throughput ion exchange purification of positively charged recombinant protein in the presence of negatively charged dextran sulfate
Biotechnol Prog, 30(2), 516-20
2012Zenix SEC-300, 7.8 x 200AntibodyAglycosylated antibodies and antibody fragments produced in a scalable in vitro transcription-translation system
mAbs, Volume 4, Issue 2, pages 217-225
2011Zenix SEC-300, 7.8 x 300AntibodyAntibody solubility behavior in monovalent salt solutions reveals specific anion effects at low ionic strength
Journal of Pharmaceutical Sciences, Volume 101, Issue 3, pages 965-977
2013Zenix SEC-300, 7.8 x 300Bispecific AntibodyKnobs-into-holes antibody production in mammalian cell lines reveals that asymmetric afucosylation is sufficient for full antibody-dependent cellular cytotoxicity
MAbs, 5(6), 872-81
2014Zenix SEC-300, 7.8 x 300ProteinConverting a Binding Protein into a Biosensing Conformational Switch Using Protein Fragment Exchange
Biochemistry, 53 (34), pp 5505-5514
2014Zenix SEC-300, 7.8 x 300Protein-KinaseProbing Kinase Activation and Substrate Specificity with an Engineered Monomeric IKK2
Biochemistry, 53(12), 2064-73
2016Zenix-C SEC-150InsulinContribution of TyrB26 to the Function and Stability of Insulin. Structure-activity relationships at a conserved hormone-receptor interface
Journal of Biological Chemistry, April 26, 2016, M115.708347.
2016Zenix-C SEC-300ADC, Fusion ProteinTargeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free-Protein Synthesis
Mol Cancer Ther. 2016 Jun;15(6):1291-300. doi: 10.1158/1535-7163
2015Zenix-C SEC-300AntibodyIntrinsic fluorescence-based at situ soft sensor for monitoring monoclonal antibody aggregation
Biotechnology Progress
2017Zenix-C SEC-300AntibodyEfficient generation of single domain antibodies with high affinities and enhanced thermal stabilities
Scientific Reports 7, Article number: 5794 (2017) doi:10.1038/s41598-017-06277-x
2016Zenix-C SEC-300AntibodyPlant-based technologies to enable rapid response to Ebola outbreak
Engineering Conferences International, Vaccine Technology VI Proceedings
2018Zenix-C SEC-300AntibodyA bispecific antibody that targets IL-6 receptor and IL-17A for the potential therapy of patients with autoimmune and inflammatory diseases
The Journal of Biological Chemistry 293, 9326-9334. 10.1074/jbc.M117.818559
2015Zenix-C SEC-300Antibody, IgEA single glycan on IgE is indispensable for initiation of anaphylaxis
J. Exp. Med. 2015 Vol. 212 No. 4 457–467
2017Zenix-C SEC-300Fusion ProteinImprovement of Pharmacokinetic Profle of TRAIL via Trimer-Tag Enhances its Antitumor Activity in vivo
Sci Rep. 2017 Aug 21;7(1):8953. doi: 10.1038/s41598-017-09518-1.
2016Zenix-C SEC-300PeptideGenetic fusion of human FGF21 to a synthetic polypeptide improves pharmacokinetics and pharmacodynamics in a mouse model of obesity
Br J Pharmacol. 2016 Jul;173(14):2208-23. doi: 10.1111/bph.13499.
2015Zenix-C SEC-300ProteinImpact of pH on molecular structure and surface properties of lentillegumin-like protein and its application as foam stabilizer
Colloids and Surfaces B: Biointerfaces 132 (2015) 45–53
2015Zenix-C SEC-300ProteinCharacterization and quantification of histidine degradation in therapeutic protein formulations by size exclusion-hydrophilic interaction two dimensional-liquid chromatography with stable-isotope labeling mass spectrometry
Journal of Chromatography A Volume 1426, 24 December 2015, Pages 133–139
2015Zenix-C SEC-300ProteinAutomated two-step chromatography using an ÄKTA equipped with in-line dilution capability
Journal of Chromatography A Volume 1424, 11 December 2015, Pages 51–58
2016Zenix-C SEC-300Protein, DNA/RNAPharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice
Nucleic Acid Therapeutics, March 31, 2016
2016Zenix-C SEC-80Polymeric SubstancesDevelopment of a Simple Nonbiological Method for Converting Lignin-Derived Aromatics into Nonaromatic Polymeric Substances with Fluorescent Activity
ACS Sustainable Chem. Eng., 2016, 4 (8), pp 4411–4416 DOI: 10.1021/acssuschemeng.6b01009

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